Supercritical fluid systems require a pump for transferring liquid carbon dioxide. JASCO offers the PU-2080-CO2 for analytical applications, the PU-2086-CO2 for applications ranging from analysis to preparative isolation, and the PU-2088-CO2 for high-volume, preparative isolation.

Whichever SFC system you choose, from analytical to semi-prep to prep scale, JASCO has an SFC fraction collection system to match your needs.

Supercritical fluid systems that use carbon dioxide add a modifier solvent when boosting the degree of extraction freedom. Achieving a stabilized compositional ratio (0.1 to 50%) is crucial to performing separation analysis, requiring a pump that performs stable fluid transfer. The PU-2080, PU-2085, PU-2086, PU-2088, and PU-2089 transfer pumps renowned for the use in HPLC, are the optimal choice for pumping modifier solvent.

When using supercritical carbon dioxide as a mobile phase, it replaces the content of the sample loop with supercritical carbon dioxide with each injection. Continuous introductions of samples requires the aspiration of the next sample after safely discharging the carbon dioxide in the sample loop and fully replacing it with an organic solvent. The AS-2059-SF can safely discharge carbon dioxide in the sample loop and continuously inject samples. The injection method can be selected as either a fixed injection volume that fills the entire sample loop or a variable injection volume that introduces the sample in a portion of the sample loop. The variable injection volume method is also capable of full injection with zero sample loss.

Density changes due to changes in temperature have a major impact on the separation and extraction process on supercritical fluid systems. Achieving stable extraction efficiency and peak retention times requires the use of an oven to precisely control extraction vessels and regulate column temperature. JASCO offers the CO-2060, which is capable of temperature control at or below room temperature and the CO-2065 and SFC-Sro. The SFC-Sro is designed for temperature control for cup-shaped, high-pressure vessels and it includes a mixing function.

Changes in pressure can greatly vary the characteristics of SFC. Achieving extraction and chromatograms with high reproducibility on a supercritical fluid system requires a device that can perform pressure control in a stable manner. JASCO offers the BP-2080, which is capable of automatic pressure control, and the BP-2080-M, which is capable of manual pressure control.

Evaluating optical characteristics under a supercritical state requires a detector and a high-pressure resistant cell. Monitoring samples in supercritical fluid is possible by replacing the flow cell section of JASCO’s liquid chromatography detector with a high-pressure resistant cell.

Achieving extractions and chromatograms with high reproducibility on a supercritical fluid system requires stable temperature control.