Pump Options: Isocratic, Binary and  Quaternary
Flow Rate: Up to 10 mL / min
Operating Pressure: Up to 500 Bar
Degassing: Vacuum (Option)
Solvents: 2, 4, 6 or 10

Pump Options: Isocratic, Binary and  Quaternary
Flow Rate: Up to 4 mL / min
Operating Pressure: Up to 700 Bar
Degassing: Vacuum (Option)
Solvents: 2, 4, 6 or 10

Pump Options: Isocratic, Binary and  Quaternary
Flow Rate: Up to 2 mL / min
Operating Pressure: Up to 1,300 Bar
Degassing: Vacuum (Option)
Solvents: 2, 4, 6 or 10

Pump Options: Isocratic, Binary
Flow Rate: Up to 20 mL / min (PU-4086)
Flow Rate: Up to 50 mL / min (PU-4087)
Operating Pressure: Up to 500 Bar
Degassing: Vacuum (Option)
Solvents: 2, 4, 6 or 10

The unique expansion bays in the pump platform can be fitted with plug-in modules to quickly and easily transform a simple isocratic pumping system into a sophisticated multi-solvent delivery system by installing a second pump, degasser, quaternary gradient unit, solvent selection valve or dynamic mixer.
Adding a second HPLC pump module enables an isocratic pump to be upgraded to a dual pump system for either binary gradient or two isocratic flows. The single-unit design of the quaternary gradient solvent delivery system including low internal volume vacuum degasser.

The PU-4000 Series pumps are normally used as part of a complete HPLC system, however for applications that require stand-alone operation, each instrument has its own keypad and can be controlled using a simple RS232 protocol and/or contact closures (TTL) to start and stop the pump.

The problems caused by pressure variations in solvent delivery when switching between two pump heads in a double reciprocating pump are virtually eliminated with JASCO’s unique asymmetric design that precisely controls the cross-over points of the plungers. The LC-4000 series analytical pumps offer flow rate precision with RSDs of better than 0.05% (difficult to achieve with commercially available pumps).

The PU-4180 and 4185 pumps operate at pressures up to 70 MPa (700bar), typically used with RHPLC for core-shell columns or similar micro packing materials as well as for use with conventional HPLC. The PU-4280/85 UHPLC pumps operate at pressures up to 130 MPa (1300 bar) for columns with particle sizes of less than 2 μm.

The PU-4180/85 and PU-4280/85 can be configured for single pump gradient and multiple pump gradient operation. The single pump quaternary gradient module offers excellent gradient formation for up to four solvents. A newly designed 4-way valve for switching the solvents is synchronized to the operation of the pump motor control – ‘variable cycle adaption’ optimizes delivery according to gradient resolution and flow rate. This highly efficient quaternary gradient can be applied across a wide flow-rate range. Binary and ternary gradient (using 2 or 3 pumps) with optional built-in degasser can be used for fast cycle high-resolution gradient formation; the gradient response time is superior to the single pump quaternary gradient system.

Multi-pump gradient mixing is done using a variable speed dynamic mixer with a range of a small volume mixing chambers to provide the smallest possible dead volume, offering higher mixing efficiencies for all HPLC solvents. The optional in-line TERA mixer is a turbulent-flow solvent mixer uniquely designed to offer high efficiency mixing with minimal dead volume.

The in-line vacuum solvent degasser uses a Teflon AF membrane with a hold-up volume of only 400μL (per solvent line); for fast solvent priming with minimal waste. Despite its small size, the new degasser offers more effective and stable degassing than larger previous generation models. A degasser for preparative HPLC is also available.