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Semi-Preparative SFC

The SP-4000 Semi-preparative SFC Hybrid system crosses the divide between analytical SFC and prep SFC offering the best of both techniques. With flow rates from 1 mL/min up to 20mL/min this system can be used with 4.6mm columns for high quality analytical separations and with 10mm columns for excellent sample isolation and purification.

Semi-Prep SFC

SP-4000 Features

Analytical to Semi-preparative Flow Rates

Using columns from 4.6 to 10 mm ID, the SP-4000 Semi-Preparative SFC System can be used for separation and purification up to several 100 mg per day of sample material.

Typical Purification range

Analytical and semi-preparative flow rates from 1mL/min to 20mL/min for purification of samples up to 100s of mg

Optional Modifier Pumps

Optional two flow rate scale modifier pumps for fine tuning modifier composition.

Column Switching

Six or ten column switching for automatic selection for method development.

Solvent Switching

Six or ten modifier solvent selection for method development.

High-Capacity Column Oven

High capacity column oven for up to 6 x 10mm columns, with an option for use of 3 column ovens for even greater flexibility.

High Recovery Rate

Patented individual MCS MicroCyclone fraction collection system for sample collection without cross contamination.

Powerful Software Options

Two software options include ChromNav and SF-Nav for simple control with powerful fractionation algorithms.

Wide Range of Detectors

Wide range of detectors including UV-Visible, PDA, Mass Spec, ELSD,  FID and Circular Dichroism.

High-Throughput Fraction Collection System

Fraction collection with 8 fraction valve or open bed fraction collector.

Dynamic Back Pressure Regulator

Patented dynamic back pressure regulator for accurate control of pressure for accurate and reproducible separations.

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